Article

Genetic inhibition of interleukin-6 receptor signaling and Covid-19

2020-07-19

Abstract excerpt

There are few effective therapeutic options for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Early evidence has suggested that IL-6R blockers may confer benefit, particularly in severe coronavirus disease 2019 (Covid-19). We leveraged large-scale human genetic data to investigate whether IL6-R blockade may confer therapeutic benefit in Covid-19. A genetic instrument cons...

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Literature Corpus work: f4ec13f7-725e-507f-8bdc-c8626689d9ef
DOI: 10.1101/2020.07.17.20155242

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