Article
Assessing the potential correlation of polymorphisms in the IL6R with relative IL6 elevation in severely ill COVID-19 patients'.
Cytokine - 1 Dec 2021
Smieszek Sandra P, Przychodzen Bartlomiej P, Polymeropoulos Vasilios M, Polymeropoulos Christos M, Polymeropoulos Mihael H
Abstract excerpt
BACKGROUND: Elevated Interleukin-6 (IL-6) may play an important role in the pathophysiology of COVID-19 yet attenuated response is not seen across all severe patients. We aimed to determine the effect of IL-6 baseline levels and other clinical variables on mortality and outcomes in hospitalized COVID-19 patients as well as to explore genetic variants associated with attenuated IL-6 response. METHODS: Baseline...
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