Article

AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia <i>in vivo</i> .

2024-09-15

Abstract excerpt

The lack of regeneration in the human central nervous system (CNS) has major health implications. To address this, we previously used transgenic mouse models to show that neurogenesis can be stimulated in the adult mammalian retina by driving regeneration programs that other species activate following injury. Expression of specific proneural factors in adult Müller glia causes them to re-enter the cell cycle and g...

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Literature Corpus work: f4ebfe24-d6a1-5128-b42b-f40e8292e5fc
DOI: 10.1101/2024.09.13.612930

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