Article

Adult organotypic brain slice cultures recapitulate extracellular matrix remodelling in haemorrhagic stroke

2025-07-16

Abstract excerpt

1. Haemorrhagic stroke is a devastating condition characterised by vessel rupture and free blood within the brain parenchyma or cerebrospinal fluid (CSF) filled spaces. Across the major subtypes of haemorrhagic stroke (subarachnoid, intracerebral, and intraventricular haemorrhages), the presence of blood in the CSF generates significant tissue damage in the first 72 hours after the event, known as early brain inju...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f4a02dcd-a7fc-578c-8c08-3f5ce5bf87ff
DOI: 10.1101/2025.07.15.665021

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Adult organotypic brain slice cultures recapitulate extracellular matrix remodelling in haemorrhagic strokeDOI 10.1101/2025.07.15.665021Read

Spatiotemporal heterogeneity and protective polarization of astrocytes depending on intercellular interaction after intracerebral hemorrhageSemantic proximity Read

Vascularized Brain Assembloids with Enhanced Cellular Complexity Provide Insights into The Cellular Deficits of TauopathySemantic proximity Read

Single Cell Immuno-Laser Microdissection Coupled to Label-Free Proteomics to Reveal the Proteotypes of Human Brain Cells After Ischemia.Semantic proximity Read

Injury-induced CTE-like pathology emerges in a human multicellular <i>in vitro</i> brain model and reveals mitochondrial and neurovascular regulationSemantic proximity Read

Spatiotemporal transcriptomic maps of mouse intracerebral hemorrhage at single-cell resolutionSemantic proximity Read

Secondary single-cell transcriptomic analysis reveals common molecular signatures of cerebrovascular injury between traumatic brain injury and agingSemantic proximity Read

Pulsed Electromagnetic Fields Protect Against Brain Injury After Intracerebral Hemorrhage: Involvement Of Anti-Inflammatory Processes And Hematoma Clearance Via CD36Semantic proximity Read

A molecular brain atlas reveals cellular shifts during the repair phase of strokeSemantic proximity Read

Brain Injury: Response to Injury Wound Healing Mechanisms and Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes MellitusSemantic proximity Read

Vascularized Brain Organoid: A Versatile Platform Models Brain Cancer and Traumatic Brain InjurySemantic proximity Read

Discovering Haematoma-Stimulated Circuits for Secondary Brain Injury after Intraventricular Haemorrhage by Spatial Transcriptome AnalysisSemantic proximity Read

The neurovascular extracellular matrix in health and diseaseSemantic proximity Read