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Shared Genetic Architecture and Causal Relationship Between Diabetes, Glycemic Traits, and Cerebral Small Vessel Disease

2026-04-19

Abstract excerpt

<h4>Background</h4> Type 2 diabetes mellitus (T2DM) has long been considered a risk factor for cerebral small vessel disease (cSVD), yet the exact relationship between glycemic markers and cSVD remains unclear. This study explores the genetic overlap and causal associations between T2DM, glycemic indices, and cSVD phenotypes using genome-wide association studies (GWAS). <h4>Methods</h4> Using large consortium-ba...

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Literature Corpus work
f46f53e1-d14d-5999-ad6e-8b1328e259a1
DOI
10.64898/2026.04.16.26351065
Open publication

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