Article

cSVI-subtype: a GWAS-anchored, vascular-centered framework for molecular subtype barcode discovery in cerebral small vessel disease

2026-06-08

Abstract excerpt

<title>Abstract</title> <p> <bold>Motivation:</bold> Cerebral small vessel disease (cSVD) is still classified mainly by clinical phenotypes and neuroimaging features, which provide limited molecular resolution for robust and transferable subtype definition. We developed cSVI-subtype to derive compact and reproducible molecular subtype barcodes for cSVD by integrating human genetics with cross-species single-cel...

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Literature Corpus work: 1fd10e68-daad-5811-a8b8-c224f6628272
DOI: 10.21203/rs.3.rs-9937210/v1

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