Article

Integration of GWAS and multi-omic QTLs identifies uncharacterized COVID-19 gene-biotype and phenotype associations

2024-09-05

Abstract excerpt

To better understand COVID-19 pathobiology and to prioritize treatment targets, we sought to identify human genes influencing genetically driven disease risk and severity, and to identify additional organismal-level phenotypes impacted by pleiotropic COVID-19-associated genomic loci. To this end, we performed ancestry-aware, trans-layer, multi-omic analyses by integrating recent COVID-19 Host Genetics Initiative g...

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Literature Corpus work: f466e68d-c2e1-5296-9b2b-ec4ce3bed444
DOI: 10.1101/2024.09.05.24313137

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