Article

Multi-trait and multi-ancestry genetic analysis of comorbid lung diseases and traits improves genetic discovery and polygenic risk prediction

2024-08-26

Abstract excerpt

While respiratory diseases such as COPD and asthma share many risk factors, most studies investigate them in insolation and in predominantly European ancestry populations. Here, we conducted the most powerful multi-trait and -ancestry genetic analysis of respiratory diseases and auxiliary traits to date. Our approach improves the power of genetic discovery across traits and ancestries, identifying 44 novel loci as...

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Literature Corpus work: 3057450e-f8a6-5941-a0c9-18cfb95bc1e5
DOI: 10.1101/2024.08.25.24312558

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