Article

An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

2020-12-22

Abstract excerpt

While genome-wide associations studies (GWAS) have successfully elucidated the genetic architecture of complex human traits and diseases, understanding mechanisms that lead from genetic variation to pathophysiology remains an important challenge. Methods are needed to systematically bridge this crucial gap to facilitate experimental testing of hypotheses and translation to clinical utility. Here, we leveraged cros...

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Literature Corpus work: 2dffeab7-a637-582c-8a0d-09c538f9d8c5
DOI: 10.1101/2020.12.20.20248572

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