Article

Context-specific eQTLs reveal causal genes underlying shared genetic architecture of critically ill COVID-19 and idiopathic pulmonary fibrosis

2024-07-14

Abstract excerpt

<h4>SUMMARY</h4> Most genetic variants identified through genome-wide association studies (GWAS) are suspected to be regulatory in nature, but only a small fraction colocalize with expression quantitative trait loci (eQTLs, variants associated with expression of a gene). Therefore, it is hypothesized but largely untested that integration of disease GWAS with context-specific eQTLs will reveal the underlying genes...

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Literature Corpus work: aebdeeb7-fe4e-5f1c-8a65-6e13bc1fb52d
DOI: 10.1101/2024.07.13.24310305

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