Article
Long distance PELDOR measurements on the histone core particle.
Journal of the American Chemical Society - 4 Feb 2009
Ward Richard, Bowman Andrew, El-Mkami Hassane, Owen-Hughes Tom, Norman David G
Abstract excerpt
The nucleosome core particle is the fundamental unit of chromatin structure and at its heart is the histone core octamer composed of histones H4, H3, H2A and H2B. To understand the structure dynamics and function of chromatin it is important to be able to probe the structures of its component parts in a variety of ways. Site directed spin-labeling technology has enabled the insertion of nitroxide spin labels at...
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