Article

SOX9 reactivation in cancer vessels shapes the tumor micro-environment through hypoxia and immune depletion promoting tumor growth and metastasis

2024-11-29

Abstract excerpt

<title>Abstract</title> <p>The development of new vascular structures is a pre-requisite for tumor growth and spread. This process is often disorganised and produces immature and leaky vessels and relies at least in part on the activity of endovascular progenitor cells (EVPs), residing in vessel walls and giving rise to mature endothelial cells in <italic>de novo</italic> blood vessel networks in the tumor. <ital...

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Literature Corpus work: f433e7f5-eff3-50b4-b808-fd3d79f482ae
DOI: 10.21203/rs.3.rs-5457583/v1

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