Article

Emerging single cell endothelial heterogeneity supports sprouting tumour angiogenesis and growth

2021-06-10

Abstract excerpt

<h4>SUMMARY</h4> Blood vessels supplying tumors are often dysfunctional and generally heterogeneous. The mechanisms underlying this heterogeneity remain poorly understood. Here, using multicolor lineage tracing, in vivo time-lapse imaging and single cell RNA sequencing in a mouse glioma model, we identify tumour-specific blood endothelial cells that originate from cells expressing the receptor for colony stimula...

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Literature Corpus work: af3487c6-b516-5ad8-94a4-6aae71160ec6
DOI: 10.1101/2021.06.09.447719

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