Article

Single-cell RNA sequencing reveals functional heterogeneity and sex differences of glioma-associated brain macrophages

2019-08-30

Abstract excerpt

Microglia are resident myeloid cells in the central nervous system (CNS) that control homeostasis and protect CNS from damage and infections. Microglia and peripheral myeloid cells accumulate and adapt tumor supporting roles in human glioblastomas that show prevalence in men. Cell heterogeneity and functional phenotypes of myeloid subpopulations in gliomas remain elusive. Single-cell RNA sequencing (scRNA-seq) of...

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Literature Corpus work: f4338801-d534-5cec-a656-5ae9cf387cb6
DOI: 10.1101/752949

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