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RNA sequence analysis reveals ITGAL/CD11A as a stromal regulator of murine low-grade glioma growth

24 May 2021

Abstract excerpt

BACKGROUND: Emerging insights from numerous laboratories have revealed important roles for nonneoplastic cells in the development and progression of brain tumors. One of these nonneoplastic cellular constituents, glioma-associated microglia (GAM), represents a unique population of brain monocytes within the tumor microenvironment that have been reported to both promote and inhibit glioma proliferation. To...

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PMID: 34043012
DOI: 10.1093/neuonc/noab130

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