Article

Neutrophils Mediate Kidney Inflammation Following Acute Skin Exposure to UVB Light

2020-05-28

Abstract excerpt

Photosensitivity to ultraviolet (UV) light affects up to ~80% of lupus patients and can exacerbate local skin disease as well as systemic disease, including lupus nephritis. While neutrophils have been implicated in local tissue injury in lupus in response to immune complex deposition, whether and how they play a role in photosensitivity induced systemic disease is unknown. Here, we show that following skin exposu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f40abdd2-0380-546d-8625-9168d68aa564
DOI: 10.1101/2020.05.25.115204

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Neutrophils Mediate Kidney Inflammation Following Acute Skin Exposure to UVB LightDOI 10.1101/2020.05.25.115204Read

Neutrophil Extracellular Traps Drive a skin–kidney inflammatory axis in UVB-Irradiated Lupus-Prone MiceSemantic proximity Read

Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes.Semantic proximity Read

Neutrophil migration: moving from zebrafish models to human autoimmunitySemantic proximity Read

The Phenotypes and Functions of Neutrophils in Systemic Sclerosis.Semantic proximity Read

Keratin 17- and PKCα-dependent transient amplification of neutrophil influx after repeated stress to the skinSemantic proximity Read

The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupusSemantic proximity Read

More Than Effects in Skin: Ultraviolet Radiation-Induced Changes in Immune Cells in Human BloodSemantic proximity Read

Neutrophils impaired by anti-galectin-3 antibodies elicit inflammation of endothelial cells to aggregate the development of lupus cutaneous vasculitis.Semantic proximity Read

The chemokine network in systemic lupus erythematous nephritis.Semantic proximity Read

Neutrophil FcγRI expression as a determinant of oxidative responses in human bloodSemantic proximity Read

Quaternary Ammonium Compound Disinfectants Reduce Lupus-Associated Splenomegaly by Targeting Neutrophil Migration and T-Cell Fate.Semantic proximity Read

L22. Crescent formation: unraveling local mediators that break glomerular epithelial cell tolerance to immune injury.Semantic proximity Read