Article

Neutrophil Extracellular Traps Drive a skin–kidney inflammatory axis in UVB-Irradiated Lupus-Prone Mice

2023-12-23

Abstract excerpt

<h4>ABSTRACT</h4> Neutrophil extracellular traps (NETs) are major pathogenic effectors in chronic systemic lupus erythematosus (SLE) pathogenesis, but how they mediate acute, UVB-triggered skin inflammation and subsequent systemic injury remains poorly defined. Using UVB-irradiated lupus-prone mice, we identified an acute NETosis-driven skin-kidney inflammatory axis linking photosensitivity to renal inflammation....

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Literature Corpus work: 85368a7c-e510-5e3b-821f-0eb1fb985236
DOI: 10.1101/2023.12.23.572573

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