Article
The chemokine network in systemic lupus erythematous nephritis.
Frontiers in bioscience : a journal and virtual library - 1 Jan 2008
Rovin Brad H
Abstract excerpt
In response to renal immune complex accumulation in systemic lupus erythematosus (SLE), monocytes, T lymphocytes, and neutrophils infiltrate the kidney and mediate tissue injury and renal dysfunction. Chemotactic factors induced by immune complexes are responsible for recruiting these inflammatory cells to the kidney. Considerable attention has focused on the role of the chemokine network in regulating renal...
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