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Article

The Phenotypes and Functions of Neutrophils in Systemic Sclerosis.

Biomolecules - 25 Aug 2024

Luo Jiao, Xie Zhongming, Duan Lihua

Abstract excerpt

Systemic sclerosis (SSc) is a chronic disease of the connective tissue characterized by its multifaceted impact on various bodily systems, yet its precise cause remains elusive. Central to its pathology are abnormal immune activation, vasculopathy, and consequent fibrosis affecting both the skin and internal organs. The intricate interplay between the innate and adaptive immune systems significantly influences...

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Fibrosis
Immunity, Innate
Neutrophils
Phenotype
Scleroderma, Systemic

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PMID: 39334819
DOI: 10.3390/biom14091054
PMCID: PMC11429774

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