Article
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.
Nucleic acids research - 1 Mar 2009
Ryu Gil-Mi, Song Pamela, Kim Kyu-Won, Oh Kyung-Soo, Park Keun-Joon, Kim Jong Hun
Abstract excerpt
We define phosphovariants as genetic variations that change phosphorylation sites or their interacting kinases. Considering the essential role of phosphorylation in protein functions, it is highly likely that phosphovariants change protein functions. Therefore, a comparison of phosphovariants between individuals or between species can give clues about phenotypic differences. We categorized phosphovariants into...
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