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Article

Untargeted metabolomics unravels functionalities of phosphorylation sites in Saccharomyces cerevisiae.

BMC systems biology - 15 Nov 2016

Raguz Nakic Zrinka, Seisenbacher Gerhard, Posas Francesc, Sauer Uwe

Abstract excerpt

BACKGROUND: Coordinated through a complex network of kinases and phosphatases, protein phosphorylation regulates essentially all cellular processes in eukaryotes. Recent advances in proteomics enable detection of thousands of phosphorylation sites (phosphosites) in single experiments. However, functionality of the vast majority of these sites remains unclear and we lack suitable approaches to evaluate functional...

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PMID: 27846849
DOI: 10.1186/s12918-016-0350-8
PMCID: PMC5109706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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