Article

Comprehensive Assessment of Initial Adaptation of ESBL Positive ST131 <i>Escherichia coli</i> to Carbapenem Exposure

2024-07-31

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> It remains unclear how high-risk Escherichia coli lineages, like sequence type (ST) 131, initially adapt to carbapenem exposure in their progression to becoming carbapenem resistant. <h4>Methods</h4> Carbapenem mutation frequency was measured in multiple subclades of extended-spectrum β-lactamase (ESBL) positive ST131 clinical isolates using a fluctuation assay followed b...

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Literature Corpus work: f3c0625a-a77c-59f4-836f-2ca796645253
DOI: 10.1101/2024.07.31.606066

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