Article

Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of <i>Escherichia coli</i> ST131

2016-02-09

Abstract excerpt

Escherichia coli ST131 is the most frequently isolated fluoroquinolone resistant (FQR) E. coli clone worldwide and a major cause of urinary tract and bloodstream infections. Although originally identified through its association with the CTX-M-15 extended-spectrum β-lactamase resistance gene, global genomic epidemiology studies have failed to resolve the geographical and temporal origin of the ST131 ancestor. Her...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a805682b-3ffb-57a9-9cab-3ddeaf3d5fce
DOI: 10.1101/039123

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of <i>Escherichia coli</i> ST131DOI 10.1101/039123Read

Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131.Semantic proximity Read

Evolutionary History of the Global Emergence of the Escherichia coli Epidemic Clone ST131.Semantic proximity Read

Evolutionary history of the global emergence of the Escherichia coli epidemic clone ST131Semantic proximity Read

Genomic surveillance of <i>Escherichia coli</i> ST131 identifies local expansion and serial replacement of subclonesSemantic proximity Read

Global dissemination of a multidrug resistant Escherichia coli clone.Semantic proximity Read

Evolution of extended-spectrum β-lactamase-producing ST131 <i>Escherichia coli</i> at a single hospital over 15 yearsSemantic proximity Read

An Escherichia coli ST131 pangenome atlas reveals population structure and evolution across 4,071 isolates.Semantic proximity Read

The epidemic of extended-spectrum-β-lactamase-producing Escherichia coli ST131 is driven by a single highly pathogenic subclone, H30-Rx.Semantic proximity Read

The <i>cnf1</i> gene is associated to an expanding <i>Escherichia coli</i> ST131 <i>H30</i> Rx/C2 sublineage and confers a competitive advantage for host colonizationSemantic proximity Read

Insights into a multidrug resistant Escherichia coli pathogen of the globally disseminated ST131 lineage: genome analysis and virulence mechanisms.Semantic proximity Read

Mapping the evolutionary path towards multi-drug resistance in the pandemic <i>Escherichia coli</i> ST131 lineageSemantic proximity Read

Complete assembly of <i>Escherichia coli</i> ST131 genomes using long reads demonstrates antibiotic resistance gene variation within diverse plasmid and chromosomal contextsSemantic proximity Read