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Concurrence of Porin Loss and Modular Amplification of β-Lactamase Encoding Genes Drives Carbapenem Resistance in a Cohort of Recurrent <i>Enterobacterales</i> Bacteremia

2019-04-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Carbapenem resistant Enterobacterales (CRE) remain urgent antimicrobial resistance threats. Approximately half of CRE clinical isolates lack carbapenem hydrolyzing enzymes and develop carbapenem resistance through alternative mechanisms. The purpose of this study was to elucidate the development of carbapenem resistance mechanisms from clonal, recurrent extended-spectrum β-...

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Literature Corpus work
22df84ea-cd74-55f7-b462-0b6cd28e1d61
DOI
10.1101/616961
Open publication

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Concurrence of Porin Loss and Modular Amplification of β-Lactamase Encoding Genes Drives Carbapenem Resistance in a Cohort of Recurrent <i>Enterobacterales</i> BacteremiaDOI 10.1101/616961
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