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Targeting Innate Immune Signaling in Glioma-Initiating Cells Impairs Self-Renewal and Radiation-Induced Cellular Plasticity

2024-12-14

Abstract excerpt

Organisms constantly face environmental stressors that threaten their cellular and genomic integrity. In their response, pathogen-associated molecular patterns (PAMPs) and/or damage-associated molecular patterns (DAMPs) are detected by pattern recognition receptors (PRRs) and trigger the innate immune response. In this study we tested the hypothesis that DAMPs contribute to radiation-induced cellular plasticity in...

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Literature Corpus work
f3ae4c68-92fd-5bf1-aa18-37ad3e5693de
DOI
10.1101/2024.12.13.628405
Open publication

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Targeting Innate Immune Signaling in Glioma-Initiating Cells Impairs Self-Renewal and Radiation-Induced Cellular PlasticityDOI 10.1101/2024.12.13.628405
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