Article

DAMP Signaling and Immunogenic Cell Death in Glioblastoma: Radiotherapy-Induced Immune Reprogramming and Opportunities for Personalized Treatment

2026-01-05

Abstract excerpt

Glioblastoma (GBM) remains among the most treatment-refractory human malignancies, shaped by profound molecular heterogeneity, extensive genomic instability and an immunosuppressive tumor microenvironment. Radiotherapy represents a cornerstone of current management; however, its therapeutic benefit is frequently limited by adaptive resistance and ineffective antitumor immunity. Emerging evidence indicates that ion...

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Literature Corpus work: 85927596-1765-5909-9ac3-5375d13f3f7c
DOI: 10.20944/preprints202601.0307.v1

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