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Emerging Role of Glioma Stem Cells in Mechanisms of Therapy Resistance

1 Jul 2023

Abstract excerpt

Since their discovery at the beginning of this millennium, glioma stem cells (GSCs) have sparked extensive research and an energetic scientific debate about their contribution to glioblastoma (GBM) initiation, progression, relapse, and resistance. Different molecular subtypes of GBM coexist within the same tumor, and they display differential sensitivity to chemotherapy. GSCs contribute to tumor heterogeneity and...

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PMID: 37444568
DOI: 10.3390/cancers15133458

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