Article

SARS-CoV2 infection triggers reactive astrocyte states and inflammatory conditions in long-term Human Cortical Organoids

2024-04-17

Abstract excerpt

SARS-CoV2, severe acute respiratory syndrome coronavirus 2, is frequently associated with neurological manifestations. Despite the presence of mild to severe CNS-related symptoms in a cohort of patients, there is no consensus whether the virus can infect directly brain tissue or if the symptoms in patients are a consequence of peripheral infectivity of the virus. Here, we use long-term human stem cell-derived cort...

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Literature Corpus work: f3a0544b-94b6-57c9-af1c-10e6ec6f2cf0
DOI: 10.1101/2024.04.16.589036

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