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SARS-CoV-2 targets glial cells in human cortical organoids

1 May 2021

Abstract excerpt

Coronavirus disease 2019 (COVID-19) patients have manifested a variety of neurological complications, and there is still much to reveal regarding the neurotropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Human stem cell-derived brain organoids offer a valuable in vitro approach to study the cellular effects of SARS-CoV-2 on the brain. Here we used human embryonic stem cell-derived cortical...

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PMID: 33979600
DOI: 10.1016/j.stemcr.2021.01.016

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