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The genetic architecture of trabecular bone score and association with fracture: a genome-wide association and meta-analysis

2025-10-03

Abstract excerpt

<h4>Background</h4> Trabecular bone score (TBS) is a texture-based measurement derived from DXA scans, which describes the distribution of mineral across the vertebral bodies. Identifying its genetic determinants is crucial for enhancing understanding of its biological basis and clarifying its relationship with fracture risk. <h4>Methods</h4> We conducted a large-scale genome-wide association study (GWAS) of TBS...

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Literature Corpus work
f39d8072-78f7-5ae0-82c9-c0139ddfccb7
DOI
10.1101/2025.10.01.678241
Open publication

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