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Article

Identification of Novel Genetic Variants Related to Trabecular Bone Score in Community-Dwelling Older Adults.

Endocrinology and metabolism (Seoul, Korea) - 1 Dec 2020

Kong Sung Hye, Yoon Ji Won, Kim Jung Hee, Park JooYong, Choi Jiyeob, Lee Ji Hyun, Hong A Ram, Cho Nam H, Shin Chan Soo

Abstract excerpt

BACKGROUND: As the genetic variants of trabecular bone microarchitecture are not well-understood, we performed a genome-wide association study to identify genetic determinants of bone microarchitecture analyzed by trabecular bone score (TBS). METHODS: TBS-associated genes were discovered in the Ansung cohort (discovery cohort), a community-based rural cohort in Korea, and then validated in the Gene-Environment...

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PMID: 33232597
DOI: 10.3803/EnM.2020.735
PMCID: PMC7803610

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