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Article

BMD-Related Genetic Risk Scores Predict Site-Specific Fractures as Well as Trabecular and Cortical Bone Microstructure.

The Journal of clinical endocrinology and metabolism - 1 Apr 2020

Nethander Maria, Pettersson-Kymmer Ulrika, Vandenput Liesbeth, Lorentzon Mattias, Karlsson Magnus, Mellström Dan, Ohlsson Claes

Abstract excerpt

CONTEXT: It is important to identify patients at highest risk of fractures. OBJECTIVE: To compare the separate and combined performances of bone-related genetic risk scores (GRSs) for prediction of forearm, hip and vertebral fractures separately, as well as of trabecular and cortical bone microstructure parameters separately. DESIGN, SETTING, AND PARTICIPANTS: Using 1103 single nucleotide polymorphisms (SNPs)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32067027
DOI: 10.1210/clinem/dgaa082
PMCID: PMC7069346

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