Article

Cryptochrome-Timeless structure reveals circadian clock timing mechanisms

2022-07-27

Abstract excerpt

Circadian rhythms influence many behaviors and diseases 1, 2 . They arise from oscillations in gene expression caused by repressor proteins that directly inhibit transcription of their own genes. The fly circadian clock offers a valuable model for studying these processes, wherein Timeless (TIM) plays a critical role in mediating nuclear entry of the transcriptional repressor Period (PER) and the photoreceptor Cr...

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Literature Corpus work: f381e9ec-99a0-5b09-bbf7-f834f9bc448c
DOI: 10.1101/2022.07.27.501640

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