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Multi-trait genome-wide analysis identified novel risk loci and candidate drugs for heart failure

2024-03-27

Abstract excerpt

Heart failure (HF) is a common cardiovascular syndrome that poses significant morbidity and mortality risks. While genome-wide association studies reporting on HF abound, its genetic etiology remains poorly elucidated, primarily due to its inherent polygenic nature. Furthermore, these genetic insights have not been fully leveraged for the development of effective primary treatment strategies for HF. In this study,...

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Literature Corpus work
fdca5f10-9f1d-594e-8109-06ad1f2fdc47
DOI
10.1101/2024.03.24.24304812
Open publication

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Multi-trait genome-wide analysis identified novel risk loci and candidate drugs for heart failureDOI 10.1101/2024.03.24.24304812
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