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Modeling VEGF and GLUT1 Expression as Coadapted Foraging Strategies in Cancer

2026-04-17

Abstract excerpt

Natural selection acting on cancer cells within their tumor microenvironment should favor cells with fast or efficient nutrient uptake strategies. Here, we develop and analyze a game-theoretic model focusing on the coadaptation between two foraging traits: vascular endothelial growth factor (VEGF) and glucose transporter 1 (GLUT1). Studies show that VEGF and GLUT1 are often co-expressed and are associated with mor...

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Literature Corpus work
f2b4c530-5dba-5c9e-9df2-524a2caac77c
DOI
10.64898/2026.04.14.718570
Open publication

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Modeling VEGF and GLUT1 Expression as Coadapted Foraging Strategies in CancerDOI 10.64898/2026.04.14.718570
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