Article
The role of IDH1 mutated tumour cells in secondary glioblastomas: an evolutionary game theoretical view.
Physical biology - 1 Feb 2011
Basanta David, Scott Jacob G, Rockne Russ, Swanson Kristin R, Anderson Alexander R A
Abstract excerpt
Recent advances in clinical medicine have elucidated two significantly different subtypes of glioblastoma which carry very different prognoses, both defined by mutations in isocitrate dehydrogenase-1 (IDH-1). The mechanistic consequences of this mutation have not yet been fully clarified, with co...
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