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Losartan Ameliorates Coronary Neointimal Thickening via Vascular Smooth Muscle Cell Phenotype Modulation in a Mouse Model of Kawasaki Disease

2026-04-18

Abstract excerpt

<h4>Background: </h4> Patients with Kawasaki disease (KD) who develop coronary artery aneurysms (CAAs) are at increased risk of future fatal coronary events. Pharmacotherapeutic strategies to prevent coronary stenosis are still lacking. This study investigated the therapeutic effect of the angiotensin receptor blocker (ARB) losartan, on coronary artery stenosis in a murine model. <h4>Methods:</h4> Five-week-old ma...

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Literature Corpus work
f2a4d4d7-7ab4-50ae-9aa5-1c2bddd4b69b
DOI
10.20944/preprints202604.1280.v1
Open publication

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