Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of ferroptosis promotes vascular smooth muscle cell phenotypic switching and aggravates neointimal hyperplasia in mice.

Molecular medicine (Cambridge, Mass.) - 3 Oct 2022

Zhang Shunchi, Bei Yanrou, Huang Yueling, Huang Yimin, Hou Lianjie, Zheng Xi-Long, Xu Yiming, Wu Shaoguo, Dai Xiaoyan

Abstract excerpt

BACKGROUND: Stent implantation-induced neointima formation is a dominant culprit in coronary artery disease treatment failure after percutaneous coronary intervention. Ferroptosis, an iron-dependent regulated cell death, has been associated with various cardiovascular diseases. However, the effect of ferroptosis on neointima formation remains unclear. METHODS: The mouse common right carotid arteries were ligated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcysteine
Share to Cyclooxygenase 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ferroptosis

Share to Hyperplasia

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Neointima

Share to Osteopontin

Source

Open in PubMed Open full text

Identifiers

PMID: 36192693
DOI: 10.1186/s10020-022-00549-7
PMCID: PMC9528136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of ferroptosis promotes vascular smooth muscle cell phenotypic switching and aggravates neointimal hyperplasia in mice.PMID 36192693Read ↗

Macrophage-like vascular smooth muscle cells dominate early atherosclerosis and are inhibited by targeting iron regulationSemantic proximity Read ↗

APE1/Ref-1 redox function prevents VSMC phenotypic switching through KLF4 suppression.Semantic proximity Read ↗

Reactive Oxygen Species: Modulators of Phenotypic Switch of Vascular Smooth Muscle Cells.Semantic proximity Read ↗

Colchicine reduces neointima formation and VSMC phenotype transition by modulating SRF-MYOCD activation and autophagy.Semantic proximity Read ↗

Knockdown of Herp alleviates hyperhomocysteinemia mediated atherosclerosis through the inhibition of vascular smooth muscle cell phenotype switching.Semantic proximity Read ↗

HMGB1 promotes intracranial aneurysm progression by regulating vascular smooth muscle cell phenotypic switching and ferroptosis.Semantic proximity Read ↗

Activation of M3AChR (Type 3 Muscarinic Acetylcholine Receptor) and Nrf2 (Nuclear Factor Erythroid 2-Related Factor 2) Signaling by Choline Alleviates Vascular Smooth Muscle Cell Phenotypic Switching and Vascular Remodeling.Semantic proximity Read ↗

Piperlonguminine attenuates atherosclerosis in mice via phenotype switching inhibition of vascular smooth muscle cells.Semantic proximity Read ↗

Tanshinone II A attenuates vascular remodeling through klf4 mediated smooth muscle cell phenotypic switching.Semantic proximity Read ↗

F-53B stimulated vascular smooth muscle cell phenotypic switch and vascular remodeling via ferroptosis-related pathway.Semantic proximity Read ↗

Soluble epoxide hydrolase inhibitor, TPPU, attenuates progression of atherosclerotic lesions and vascular smooth muscle cell phenotypic switching.Semantic proximity Read ↗

GATA3 modulation of mitochondrial oxidative stress inhibits cerebrovascular remodeling-mediated ischemic stroke by suppressing MBVSMC phenotypic transformation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.