Article
Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease-Associated Abdominal Aortic Aneurysm.
Arteriosclerosis, thrombosis, and vascular biology - 1 May 2016
Wakita Daiko, Kurashima Yosuke, Crother Timothy R, Noval Rivas Magali, Lee Youngho, Chen Shuang, Fury Wen, Bai Yu, Wagner Shawn, Li Debiao, Lehman Thomas, Fishbein Michael C, Hoffman Hal M, Shah Prediman K, Shimada Kenichi, Arditi Moshe
Abstract excerpt
OBJECTIVE: Kawasaki disease (KD) is the most common cause of acquired cardiac disease in US children. In addition to coronary artery abnormalities and aneurysms, it can be associated with systemic arterial aneurysms. We evaluated the development of systemic arterial dilatation and aneurysms, including abdominal aortic aneurysm (AAA) in the Lactobacillus casei cell-wall extract (LCWE)-induced KD vasculitis mouse...
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