Article

Reconstructing ICAM-1-binding var genes of Plasmodium falciparum

2016-01-01

Abstract excerpt

Malaria is a major cause of morbidity and mortality globally. Severe malaria in patients infected with the most deadly species, Plasmodium falciparum, involves sequestration of P. falciparum-infected erythrocytes in the microvasculature, a process involving the interaction of numerous parasite and host factors. The highly variable gene family var encodes PfEMP1 proteins which are thought to be responsible for the...

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Literature Corpus work: f2a1e034-1edc-5681-88e1-abaa066b7c38
DOI: 10.17638/03001685

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