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Article

Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci.

BMC genomics - 27 Feb 2015

Hulur Imge, Gamazon Eric R, Skol Andrew D, Xicola Rosa M, Llor Xavier, Onel Kenan, Ellis Nathan A, Kupfer Sonia S

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with diseases of the colon including inflammatory bowel diseases (IBD) and colorectal cancer (CRC). However, the functional role of many of these SNPs is largely unknown and tissue-specific resources are lacking. Expression quantitative trait loci (eQTL) mapping identifies target genes of...

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Source

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Identifiers

PMID: 25766683
DOI: 10.1186/s12864-015-1292-z
PMCID: PMC4351699

Genes

ADCY3
ERAP2
NXPE1
REXO2
SFMBT1
UBA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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