Article

Exome sequencing directly implicates 68 genes in inflammatory bowel disease

2026-05-12

Abstract excerpt

Inflammatory bowel disease (IBD) is a chronic immune-mediated disorder of the gastrointestinal tract whose genetic basis is only partly resolved because most risk variants identified by genome-wide association studies (GWAS) lie in non-coding regions, limiting direct gene assignment and biological interpretation 1,2 . Here we analysed whole-exome and whole-genome sequencing data from 86,213 IBD cases and 478,363...

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Literature Corpus work: 23a8eecc-c982-5d78-a4a8-4124855cdf11
DOI: 10.64898/2026.05.08.26352648

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