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Deep tissue optical 3D imaging reveals preferential preservation of extra-islet β-cells in late-onset Type 1 Diabetes

2025-09-07

Abstract excerpt

As residual β-cell function may have positive effects on diabetes regulation in T1D, details on its spatial distribution and mass could provide important information for potential future therapeutic regimens. We implemented an optical 3D imaging pipeline to generate a first account of the 3D-spatial and volumetric distribution of the remaining β-cells throughout the volume of an entire human late onset T1D pancrea...

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Identifiers and source

Literature Corpus work
f2789ff6-a112-5b2a-bbf4-50c843f48b5f
DOI
10.1101/2025.09.03.673632
Open publication

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Deep tissue optical 3D imaging reveals preferential preservation of extra-islet β-cells in late-onset Type 1 DiabetesDOI 10.1101/2025.09.03.673632
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