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Article

Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors

1 Jan 2013

Abstract excerpt

Testicular cancer is the most frequent cancer in young men aged 15-40 years and accounts for 1% of all cancer diagnosed in males. Testicular germ cell tumors (TGCT) encompass a broad group of cancers, each displaying different levels of pluripotency and differentiation as well as malignancy potential. The TGCT cell of origin is thought to be a fetal germ cell that failed to correctly differentiate during...

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PMID: 23784832
DOI: 10.1387/ijdb.130028pk

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