Article

Nonlinear ridge regression improves cell-type-specific differential expression analysis

2021-01-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Epigenome-wide association studies (EWAS) and differential gene expression analyses are generally performed on tissue samples, which consist of multiple cell types. Cell-type-specific effects of a trait, such as disease, on the omics expression are of interest but difficult or costly to measure experimentally. By measuring omics data for the bulk tissue, cell ty...

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Literature Corpus work: f257697a-bd2c-58fc-ba70-6e99579329b4
DOI: 10.21203/rs.3.rs-39226/v3

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