Article

Five-Lipoxygenase-Activating Protein Mediated CYLD Attenuation is a Candidate Driver in Hepatic Malignant Lesion

2021-11-30

Abstract excerpt

<h4>Background: </h4> Hepatocellular carcinoma (HCC) is an inflammation-associated cancer. However, the lipid pro-inflammatory mediators have only been seldom investigated in HCC pathogenesis. Activation of NF-κB and expression of c-Myc are negatively regulated by cylindromatosis (CYLD) in hepatocarcinogenesis. But it remains largely unknown whether lipid pro-inflammatory mediators are involved in CYLD suppression...

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Literature Corpus work: f2517df1-48cb-5d10-8564-954d475c0ab7
DOI: 10.21203/rs.3.rs-1103655/v1

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