Article

Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signaling

2022-01-12

Abstract excerpt

<h4>Background: </h4> and Purpose Squalene epoxidase (SQLE) is a key enzyme involved in cholesterol biosynthesis, but increasing evidence reveals that SQLE is abnormally expressed in some types of malignant tumors, and the underlying mechanism remains poorly understood. Experimental Approach Bioinformatics analysis and RNA sequencing were applied to detect to differentially expressed genes in clinical HCC tumors....

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Literature Corpus work: 38995042-acbd-504b-8cdf-13a098acba02
DOI: 10.22541/au.164201880.00585800/v1

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