Article

Systematical analysis reveals the novel function of <i>Cyp2c29</i> in liver injury

2019-09-09

Abstract excerpt

As a severe lethal cancer, hepatocellular carcinoma (HCC) usually originates from chronic liver injury and inflammation, in which the discovery of key genes is important for HCC prevention. Here, we analyzed the time serial (from 0 week to 30 weeks) transcriptome data of liver injury samples in diethylnitrosamine (DEN)-induced HCC mouse model. Through expression and function analyses, we identified that Cyp2c29 w...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cf13602f-74dd-54e6-b03e-b1ea7df1f65b
DOI: 10.1101/763581

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Systematical analysis reveals the novel function of <i>Cyp2c29</i> in liver injuryDOI 10.1101/763581Read

Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma developmentSemantic proximity Read

Gene expression, regulation of DEN and HBx induced HCC mice models and comparisons of tumor, para-tumor and normal tissuesSemantic proximity Read

Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma.Semantic proximity Read

Identification and Analysis of Hub Transcriptional Factors Related to Acetaminophen-Induced Liver InjurySemantic proximity Read

Identification and Analysis of Hub Transcriptional Factors in vitro hepatocyte model of Acetaminophen- Induced Liver InjurySemantic proximity Read

The Mutational and Transcriptional Landscapes of Hepatocarcinogenesis in a Rat ModelSemantic proximity Read

Different inhibition of Nrf2 by two Keap1 isoforms α and β to shape malignant behaviour of human hepatocellular carcinomaSemantic proximity Read

Hepatic Premalignant Alterations Triggered by Human Nephrotoxin Aristolochic Acid I in CaninesSemantic proximity Read

Clock gene Per2 as a controller of liver carcinogenesis.Semantic proximity Read

Network Analysis for the Identification of Hub Genes and Related Molecules as Potential Biomarkers Associated With the Differentiation of Bone Marrow-derived Stem Cells Into HepatocytesSemantic proximity Read

Identification of the potential therapeutic target gene UBE2C in human hepatocellular carcinoma: An investigation based on GEO and TCGA databasesSemantic proximity Read

Unraveling the Molecular Links between Benzopyrene Exposure, NASH, and HCC: An Integrated Bioinformatics and Experimental StudySemantic proximity Read