Article

A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profiling

2023-03-01

Abstract excerpt

<h4>ABSTRACT</h4> Numerous techniques have been employed to deconstruct the heterogeneity observed in normal and diseased cellular populations, including single cell RNA sequencing, in situ hybridization, and flow cytometry. While these approaches have revolutionized our understanding of heterogeneity, in isolation they cannot correlate phenotypic information within a physiologically relevant live-cell state, wi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 34f7e085-f73d-53fb-9d6f-9e57bf2ed6e9
DOI: 10.1101/2023.02.28.530493

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profilingDOI 10.1101/2023.02.28.530493Read

A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profiling.Semantic proximity Read

Automated Intelligent Microscopy for Phenotype Identification, Spatial Localization, and Retargeting of Cells.Semantic proximity Read

Linking the genotypes and phenotypes of cancer cells in heterogenous populations via real-time optical tagging and image analysis.Semantic proximity Read

Spatially-Resolved Live Cell Tagging and Isolation Using Protected Photoactivatable Cell DyesSemantic proximity Read

Exploiting Single-Cell Tools in Gene and Cell TherapySemantic proximity Read

Scalable longitudinal imaging and transcriptomics of cells in dynamic enclosuresSemantic proximity Read

Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes.Semantic proximity Read

Single-Cell Omics: A Review of Technologies, Instrumentation, Data Analysis, and ApplicationsSemantic proximity Read

Defining Cell Identity with Single-Cell Omics.Semantic proximity Read

Imaging vs Nonimaging Raman Spectroscopy for High-Throughput Single-Cell Phenotyping.Semantic proximity Read

Integrating single-cell RNA-seq and imaging with SCOPE-seq2Semantic proximity Read

AI-driven Deep Visual Proteomics defines cell identity and heterogeneitySemantic proximity Read