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Artificial intelligence-powered spatial analysis of tumor-infiltrating lymphocytes as a predictive biomarker for immune checkpoint inhibitors in advanced biliary tract cancer

2024-01-10

Abstract excerpt

<title>Abstract</title> <p>The combination of anti-PD-1/L1 with gemcitabine and cisplatin (GemCis) has recently shown significant survival benefits in randomized phase 3 trials for advanced biliary tract cancer (BTC). However, no biomarker predictive of benefit has been established for anti-PD-1/L1 in BTC. Here, we evaluated tumor-infiltrating lymphocytes (TILs) using artificial intelligence-powered immune phenot...

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Literature Corpus work: f2212d6c-df2c-5c72-9e9c-7c8d4cae6779
DOI: 10.21203/rs.3.rs-3839367/v1

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